Job Details

  • Title: Assay Development Scientist
  • Code: RCI-PFE-16823-1
  • Location: La Jolla California (CA) 92121
  • Posted Date: 10/08/2019
  • Duration: 18 Months
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  Job Description

  • The successful candidate will join a dynamic, multi-disciplinary team of scientists in the Oncology Translational Research – Tumor Morphology Group, playing a key role in the development and conduct of predictive biomarker assays in human study samples.
  • An Assay Development Scientist serves as a technical expert and supports the rapidly expanding oncology and immuno-oncology portfolio.

Responsibilities:

  • Carry out experiments to help develop, validate and execute biomarker assays to support Phase I/II clinical studies.
  • Serve as a technical resource within the TMG for cell culture and preparation of RNA and protein.
  • Explore novel concepts and innovative technologies to expand the group’s biomarker discovery capabilities
  • Ensure all tasks and responsibilities are carried out according to scientific and ethical standards.
  • Interface with colleagues in matrixed diagnostic teams.
  • Manage sample work flows including sample accessioning and archiving.
  • Gather, interpret, analyze data.
  • Keep up to date with relevant scientific and technical developments.

Qualifications:

  • BS in biological science with 3+ years of experience in assay development/validation with a focus on cancer biology and biomarkers
  • Experience in immunohistochemistry development in human tumors
  • Experience working with human samples, including sample prep of various types of tumor specimens
  • Experience in cell culture and current molecular biology techniques, including qRT-PCR, western blotting, and gene expression profiling.
  • Current knowledge of oncology research, drug discovery and development
  • Experience with next generation DNA/RNA sequencing, NanoString/HTG analysis of mRNA strongly preferred.
  • Experience with and/or comfortable handling mice.
  • Ability to effectively interact and collaborate with other scientists, both within the group and in other groups; excellent communication and interpersonal skills.