Job Details

  • Title: Scientist II
  • Code: RCI-03523
  • Location: Waltham Massachusetts (MA) 02451
  • Posted Date: 01/26/2021
  • Duration: 6 Months
Talk to our Recruiter

  Job Description

Responsibilities will include, but are not limit to, the following:

  • Provides direct on-site early formulation development support to enable efficacy, PK, and toxicology studies for small molecule Drug Discovery efforts.
  • Provides drug substance characterization including crystallinity assessment, solubility determination, and physicochemical stability evaluation.
  • Offers solubility enhancement of poor water soluble compounds by applying various solubilization techniques.
  • Develops understanding of the impact of physiochemical and solid state properties on drug candidate performance.
  • Perform in-silico biopharmaceutical evaluation to support drugability assessment.
  • Inform and influence drug discovery team finding new chemical entities with desirable physicochemical and biopharmaceutical properties.
  • Recommends potential clinical formulation to the project team based on physicochemical and biopharmaceutical properties of the drug candidate.

Skills

  • Knowledge in discovery and preclinical formulation support, preformulation screening, solid state characterization and aiding formulation design. Analytical mindset on analyzing formulation, and hands-on experience on instruments such as HPLC, dissolution, microscope, and particle size analysis,
  • Self-motivated with capabilities in executing tasks independently, following protocols accurately, managing time efficiently, delivering formulations accurately and timely, and collaborating with other team members professionally.
  • Good written and verbal communication skills.
  • B.S./M.S./Ph.D. in pharmaceutics, pharmaceutical science, pharmaceutical chemistry or related scientific discipline required.
  • Prefer 1 to 2 years of relevant experience in discovery and preclinical support, preformulation screening, early formulation development, and solid state characterization in the pharmaceutical industry.

Education

  • Minimum BS, prefer MS or PhD, in Pharmaceutics, pharmaceutical science, pharmaceutical chemistry or related scientific discipline required.